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Fig. 3 | Respiratory Research

Fig. 3

From: Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter

Fig. 3

Tregs from EPFR-exposed mice suppresses adaptive T cell response in Air-exposed mice. a Schematic for isolation and adoptive transfer of Tregs from DCB exposed mice to Air exposed mice at 10 dpe, i.n. influenza infection and analysis of adaptive T cell response at 6 dpi. b Percentage of pulmonary CD8+ cells expressing IFNγ (Tc1) and representative flow contour plots in DCB/Flu, and Treg/Air/Flu mice in comparison to Air/Flu mice. c Percentage of pulmonary CD4+ cells expressing IFNγ (Th1) and representative flow contour plots in DCB/Flu, and Treg/Air/Flu mice in comparison to Air/Flu mice. Data are plotted as means ± SEM. *p < 0.05 and ** p < 0.01 vs Air/Flu mice. One-way ANOVA with Holm-Sidak correction for multiple comparisons

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Respiratory Research

ISSN: 1465-993X

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