Fig. 2
From: The impact of low-frequency, low-force cyclic stretching of human bronchi on airway responsiveness
Significant effects of pretreatment in bronchial tone or responsiveness during and following 1 hour of low-force cyclic stretching. Three distinct periods can be seen: during stretch (basal tone), 10 min after cyclic stretch (the post-stretch response) and the maximal tone after a dose–response to acetylcholine (ACh). In all cases, epithelium removal and L-NAME pretreatment were significantly involved