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Fig. 5 | Respiratory Research

Fig. 5

From: Increased expression of TROP2 in airway basal cells potentially contributes to airway remodeling in chronic obstructive pulmonary disease

Fig. 5

TROP2 promotes BC proliferation and wound closure in vitro. a The O.D. 450 results from the CCK-8 viability assay are plotted as a function of time for pcDNA3.1-TROP2-BCs and control cells. Cell viability in the pcDNA3.1-TROP2-BCs was significantly improved (P < 0.05). b, c Cell cycle analysis of pcDNA3.1-TROP2-BCs and control cells. Distribution of cells in G1, S and G2/M phases as determined by flow cytometry are represented graphically in a bar graph and in the standard flow diagram generated in the ModFit LT 4.0 software. d Images of wound healing assays and quantitation of results performed on pcDNA3.1-TROP2-BCs and control cell types. (P < 0.01). * P < 0.05 vs untransfected cells; # P < 0.05 vs pcDNA3.1-BCs; ** P < 0.01 vs untransfected cells; ## P < 0.01 vs pcDNA3.1-BCs

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Respiratory Research

ISSN: 1465-993X

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