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Table 3 Differentially Methylated CpG Probes Associated with COPD Among African- Americans in PA-SCOPE

From: Differential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations

Chromosome

CpG Probe

Nearest Gene

Mean Difference in Percent Methylation

p-value

FDR Adjusted p-value

5

cg16361890

MAML1

-7.8

8.19E-08

0.001

22

cg00615377

RBFOX2

-5.3

1.20E-07

0.001

9

cg12971694

CD72

-9.0

2.05E-06

0.013

12

cg22566906

GRASP

-7.8

7.27E-06

0.029

4

cg02635407

SH3TC1

-9.6

7.47E-06

0.029

11

cg25634666

FOLR3

-10.8

3.23E-05

0.080

10

cg18390025

ELOVL3

-8.4

3.40E-05

0.080

5

cg10257049

FAXDC2

-7.5

3.58E-05

0.080

19

cg27461196

FXYD1/LGI4

-11.9

4.27E-05

0.080

6

cg00333528

GABRR1

-8.0

4.43E-05

0.080

21

cg17356733

IFNGR2

-11.9

4.56E-05

0.080

17

cg24489015

LPO

-10.8

5.82E-05

0.094

  1. Data are presented in decreasing order of significance. Mean difference in percent methylation represents the mean difference in percent methylation between cases and controls; p-values were adjusted for multiple comparisons using the method of Benjamini and Hochberg