Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development

Table 3 SNPs within 5 top differentially expressed genes associated with lung function

Gene	Associated SNP	Locus	Lung function measure	Coded Allele	Direction of effect	Reference
CDC123	rs7068966	10p13	FEV₁	T	+	Soler-Artigas et al. [9]
CDC123	rs7068966	10p13	FEV₁/FVC	T	+	Soler-Artigas et al. [9]
PTCH1	rs16909898	9q22.32	FEV₁/FVC	A	+	Hancock et al. [7]
PTCH1	rs10512249	9q22.32	FEV₁/FVC	A	−	Hancock et al. [7]
TMEM163	rs1942055	2p21.3	FVC	G	−	Loth et al. [10]
FAM13A	rs2869967	4q22.1	FEV₁/FVC	T	+	Hancock et al. [7]
FAM13A	rs6830970	4q22.1	FEV₁/FVC	A	+	Hancock et al. [7]
HHIP	rs1980057	4q31.21	FEV₁/FVC	T	+	Hancock et al. [7]
	rs1032295		FEV₁/FVC	T	−	Hancock et al. [7]
	rs12504628		FEV₁	T	−	Repapi et al. [6]
	rs12504628		FEV₁/FVC	T	−	Repapi et al. [6]

ISSN: 1465-993X