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Fig. 5 | Respiratory Research

Fig. 5

From: Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats

Fig. 5

Targeted CF6 silencing alleviates hemodynamic changes and right ventricular hypertrophy in PAH rats at 4 weeks after MCT exposure. a Representative hemodynamic data (RVSP) obtained with a Labchart acquisition system. b CF6 shRNA decreased RVSP in the MCT-control group. c CF6 shRNA also reduced the RV/LV + S ratio in the MCT-treated rats. The data represent the mean ± SD. **p < 0.01 and *p < 0.05. RVSP, right ventricle systolic pressure; RV/LV + S ratio, weight ratio of the right ventricle to the left ventricle plus the septum

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Respiratory Research

ISSN: 1465-993X

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