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Table 4 Spearman’s correlation analysis between MMPs/TIMP1 ratios and emphysema sub-types

From: Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

  MMP-3/TIMP-1 MMP-7/TIMP-1 MMP-8/TIMP-1 MMP-9/TIMP-1 MMP-10/TIMP-1 MMP-12/TIMP-1
Mild CLE −0.08 −0.06 −0.05 −0.03 0.01 −0.14
Moderate CLE 0.39* 0.39* 0.44* 0.34 0.43* 0.12
Severe CLE 0.44* 0.36* 0.36* 0.28 0.40* 0.08
Panlobular 0.59*** 0.43* 0.36* 0.31 0.55** 0.33
Paraseptal 0.47** 0.50** 0.42* 0.37* 0.47** 0.15
Normal −0.37* −0.35 −0.36* −0.29 −0.44* −0.04
  1. Spearman’s rho values given
  2. N = 31. *p < 0.05; **p < 0.01; ***p < 0.001