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Table 3 Adjusted mean breathing discomfort measured using the Borg category-ratio scale at isotime after 6 weeks (full analysis set)

From: Evaluation of the effects of olodaterol on exercise endurance in patients with chronic obstructive pulmonary disease: results from two 6-week crossover studies

  

Isotime

Treatment

n

Mean time, mm:ssa

Borg (SE)

p value versus placebo

Study 1222.37

   

Baseline

  

5.27 (0.21)

 

Placebo

136

05:58

5.87 (0.19)

 

Olodaterol 5 μg

140

06:02

5.10 (0.18)

0.0007

Olodaterol 10 μg

136

06:05

5.24 (0.19)

0.0051

Study 1222.38

   

Baseline

  

5.53 (0.19)

 

Placebo

146

05:29

5.59 (0.18)

 

Olodaterol 5 μg

141

05:25

5.25 (0.18)

0.1176

Olodaterol 10 μg

140

05:22

5.52 (0.18)

0.7591

  1. aDue to differences in the number of patients between treatment groups, slight differences in mean time are observed
  2. SE standard error