Table 1 Demographics, clinical and pulmonary function data
From: Expression of toll-like receptors 2 and 4 in subjects with asthma by total serum IgE level
Normal total serum IgE (n = 29) | High total serum IgE (n = 15) | P | |
|---|---|---|---|
Age (years), mean (STD) | 51.34 (17.5) | 52.06 (15.6) | 0.894 |
Sex (% women) | 74 % | 52.94 % | 0.150 |
BMI (kg/m2), mean (STD) | 26.59 (4.45) | 27.87 (4.3) | 0.368 |
Rhinitis, % subjects (n) | 62.06 % (18) | 80 % (12) | 0.194 |
Nasal polyposis, % subjects (n) | 21.7 % (6) | 40 % (6) | 0.157 |
ACT ≥ 20, % subjects, (n) | 58.62 % | 73.33 % | 0.267 |
FEV1%, mean (STD) | 84.93 (18.4) | 77.13 (20.7) | 0.209 |
FEV1/FVC, mean (STD) | 68.8 (13.9) | 63.29 (11.8) | 0.173 |
Total IgE (UI/mL), mean (STD) | 67.5 (44.7) | 545.4 (467.8) | 0.000 |
Positive skin prick test, % subjects) | 55.17 % | 86.66 % | 0.036 |
FeNO (ppb), mean (STD) | 39.3 (34.1) | 28.8 (17.2) | 0.272 |
Patients receiving 2 or > OC within last 12 m, % subjects | 1.85 (2.8) | 2.33 (3.9) | 0.576 |
ICS dose in patients (high ICS dose: ≥ 800 μg/day Beclomethasone or equivalent), % subjects (n) | 31.03 % (9) H 34.5 %(10) M 31.03 % (9) L 3.44 % (1) N | 27 %(4) H 27 % (4) M 46 % (7) L 0 % (0) N | 0.697 |