Free light chains: potential biomarker and predictor of mortality in alpha-1-antitrypsin deficiency and usual COPD

Table 2 Linear regression analysing log cFLC in all stable patients

Variable	B (95 % CI)	R² change	F change	P (F change)
eGFR	−0.001 (−0.002–−0.001)	0.04	19.94	<0.001
Age	0.001 (0–0.003)	0.03	16.40	<0.001
Chronic bronchitis	0.033 (0.007–0.06)	0.02	9.72	0.002
FEV1% predicted	4.8 × 10⁻⁴ (0–0.001)	0.01	3.00	0.084
A1ATD	−0.09 (−0.133–−0.053)	0.03	21.10	<0.001

The table shows the regression coefficients (B) and significance of variables. The two most important variables in the model were eGFR and A1ATD

ISSN: 1465-993X