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Fig. 6 | Respiratory Research

Fig. 6

From: Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells

Fig. 6

FN mRNA expression and protein production in BSMCs and HFL-1 stimulated by rhDPP4. a rhDPP4-induced FN mRNA expression in BSMCs at 72 h. * P < .05 and ** P < .001, compared with no rhDPP4. b rhDPP4-induced FN protein production in BSMCs at 96 h. * P < .05, compared with no rhDPP4. The actual mean concentrations of FN protein (ng/mL) in BSMCs were shown in b as control = 4726.8, DPP4 (10 ng/mL) = 5903.5, DPP4 (50 ng/mL) = 6304.46, DPP4 (100 ng/mL) = 6512.1, and DPP4 (500 ng/mL) = 5903.5. c rhDPP4-induced FN mRNA expression in HFL-1 at 48 h. * P < .05, compared with no rhDPP4. d. rhDPP4-induced protein production in HFL-1 at 72 h. * P < .05, compared with no rhDPP4. The actual mean concentrations of FN protein (ng/mL) in HFL-1 were shown in b as control = 26469, DPP4 (50 ng/mL) = 28098, DPP4 (100 ng/mL) = 28777, and DPP4 (500 ng/mL) = 29737

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