Fig. 6From: Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells FN mRNA expression and protein production in BSMCs and HFL-1 stimulated by rhDPP4. a rhDPP4-induced FN mRNA expression in BSMCs at 72 h. * P < .05 and ** P < .001, compared with no rhDPP4. b rhDPP4-induced FN protein production in BSMCs at 96 h. * P < .05, compared with no rhDPP4. The actual mean concentrations of FN protein (ng/mL) in BSMCs were shown in b as control = 4726.8, DPP4 (10 ng/mL) = 5903.5, DPP4 (50 ng/mL) = 6304.46, DPP4 (100 ng/mL) = 6512.1, and DPP4 (500 ng/mL) = 5903.5. c rhDPP4-induced FN mRNA expression in HFL-1 at 48 h. * P < .05, compared with no rhDPP4. d. rhDPP4-induced protein production in HFL-1 at 72 h. * P < .05, compared with no rhDPP4. The actual mean concentrations of FN protein (ng/mL) in HFL-1 were shown in b as control = 26469, DPP4 (50 ng/mL) = 28098, DPP4 (100 ng/mL) = 28777, and DPP4 (500 ng/mL) = 29737Back to article page