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Fig. 7 | Respiratory Research

Fig. 7

From: YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodeling

Fig. 7

YKL-40 induced phosphorylation of extracellular signal related kinase (ERK), and p38 in lung fibroblast cells. Recombinant human YKL-40 protein activated ERK and p38 phosphorylaton in a dose-dependent manner (0, 1, 10, 50, 100 and 200 ng/ml for 2 h) (a); Stimulation of lung fibroblast cells with 50 ng/ml of recombinant human YKL-40 protein also induced phosphorylation of ERK and p38 in a time-dependent manner (0, 5, 15, 30, 60, 120 min) (b)

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