Fig. 5
From: C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice
Changes in pulmonary inflammation and collagen deposition in periostin-CNP Tg mice after BLM administration. Quantitative RT-PCR analysis of IL-1β (a), IL-6 (b), bFGF (c), collagen 1A (d), TIMP1 (e), and TGF-β (f) in lung tissues at 14 days after BLM administration was performed. The relative mRNA expression levels (mean of WT littermates = 1) of each cytokine in WT littermates without BLM (n = 5), periostin-CNP Tg mice without BLM (n = 6), WT littermates with BLM (n = 9), or periostin-CNP Tg mice with BLM (n = 6) are shown. Values represent means ± SEM. *P < 0.05