Table 1 Characteristics of the subjects in the lung tissue study

Subjects n

23

17

24

Male sex, %

30.4

82.4

87.5

Age, y

66.3 ± 9

65.3 ± 10

70.8 ± 7

Smoking status, pack-y

0

42.2 ± 20

49.0 ± 28

FEV_1, L

2.41 ± 0.60

2.55 ± 0.47

1.83 ± 0.53^**

FEV₁ %predicted, %

112 ± 16

92.5 ± 8.0^*

72.7 ± 18^{*, **}

FVC, L

3.05 ± 0.72

3.35 ± 0.66^*

3.04 ± 0.74^**

FVC %predicted, %

114 ± 15

98.8 ± 9.0

96.8 ± 17^*

FEV₁/FVC, %

79.2 ± 4.4

76.3 ± 4.1

59.6 ± 8.3^{*, **}

D_LCO/V_A %predicted, %^a

96.1 ± 14

89.7 ± 15

79.9 ± 22^*