| Univariate |  | Multivariable-adjusted |  |
---|---|---|---|---|
 | B-estimate (95 % CI) | P-value | B-estimate (95 % CI) | P-value |
Age | Â | Â | Â | Â |
  < 50 | Ref |  | Ref |  |
 50- <65 | 3891.1 (2985.4, 4796.7) | <0.0001 | 3117.53 (2219.7, 4015.4) | <0.0001 |
 65- <80 | 6652.1 (5449.1, 7855.1) | <0.0001 | 4176.16 (2912.7, 5439.7) | <0.0001 |
  ≥ 80 | 7109.4 (5582.7, 8636.1) | <0.0001 | 2974.40 (1606.2, 4342.6) | <0.0001 |
Gender | Â | Â | Â | Â |
 Female | Ref |  | Ref |  |
 Male | -426.92 (-1051.0, 197.2) | 0.1797 | -665.99 (-1277.8, -54.2) | <0.0001 |
Median household income | Â | Â | Â | Â |
 1st quartile (< $38,999) | Ref |  | Ref |  |
 2nd quartile ($39,000 to $47,999) | 371.8 (-1261.3, 2005.0) | 0.6550 | -273.8 (-1882.1, 1334.5) | 0.7383 |
 3rd quartile ($48,000 to $62999) | 4658.7 (2156.6, 7160.9) | 0.0003 | 2250.3 (34.0, 4466.6) | 0.0466 |
 4th quartile ($63,000 or more) | 7493.74 (3997.5, 10990.0) | <0.0001 | 4614.2 (1284.2, 7944.2) | 0.0067 |
Primary payer | Â | Â | Â | Â |
 Medicare (ref) | Ref |  | Ref |  |
 Medicaid | -2014.3 (-3242.1, -786.4) | 0.0013 | -963.2 (-2007.8, 81.3) | 0.0707 |
 Private insurance | -3725.8 (-4972.1, -2479.4) | <0.0001 | -2264.3 (-3574.4, -954.1) | 0.0007 |
 Self-pay/no charge | -7134.2 (-8265.9, -6002.6) | <0.0001 | -4291.1 (-5496.3, -3085.8) | <0.0001 |
 Other | -2313.6 (-4674.1, 47.0) | 0.0547 | -2427.7 (-4355.3, -500.1) | 0.0136 |
Patient location (residence) | Â | Â | Â | Â |
 Micropolitan/not metro | Ref |  | Ref |  |
 Metro (large or small) | 9681.5 (7392.3, 11970.6) | <0.0001 | 8000.2 (5631.0, 10369.3) | <0.0001 |
Hospital Region | Â | Â | Â | Â |
 Northeast | Ref |  | Ref |  |
 Midwest | -5464.4 (-9760.8, 1168.1) | 0.0127 | -3131.5 (-7348.2, 1085.1) | 0.1453 |
 South | 257.9 (-4333.9, 4849.7) | 0.9122 | 3009.9 (-1643.7, 7663.6) | 0.2046 |
 West | 17022.9 (11248.1, 22797.8) | <0.0001 | 18103.3 (12310.9, 23895.8) | <0.0001 |
Teaching status of hospital | Â | Â | Â | Â |
 Metropolitan non-teaching or non-metropolitan | Ref |  | Ref |  |
 Metropolitan teaching | 181.7 (-3059.2, 3422.7) | 0.9124 | -461.9 (-3862.1, 2938.4) | 0.7898 |
Comorbidities | Â | Â | Â | Â |
 CHD (ref: no) | 2094.6 (1516.9, 2672.4) | <0.0001 | 892.91 (347.7, 1438.1) | 0.0014 |
 Hyperlipidemia (ref: no) | -1748.2 (-2335.2, -1161.2) | <0.0001 | -2162.7 (-2709.3, -1616.1) | <0.0001 |
 Renal failure (ref: no) | 4756.1 (3906.7, 5605.5) | <0.0001 | 2414.5 (1672.6, 3156.4) | <0.0001 |
 CHF (ref: no) | 7385.2 (6410.1, 8360.3) | <0.0001 | 6489.5 (5491.6, 7487.4) | <0.0001 |
 Gout (ref: no) | -1128.9 (-2562.4, 304.6) | 0.1225 | -3127.6 (-4587.4, -1667.8) | <0.0001 |
 Diabetes (ref: no) | 1474.4 (853.5, 2095.3) | <0.0001 | 844.6 (247.4, 1441.7) | 0.0056 |
 Hypertension (ref: no) | 329.1 (-310.1, 968.2) | 0.3125 | -674.9 (-1341.2, -8.53) | 0.0471 |
 Osteoarthritis (ref: no) | -2524.4 (-3469.5, -1579.3) | <0.0001 | -2153.9 (-3023.9, -1283.9) | <0.0001 |