Skip to main content
Fig. 1 | Respiratory Research

Fig. 1

From: TNF-α and IL-1β-activated human mesenchymal stromal cells increase airway epithelial wound healing in vitro via activation of the epidermal growth factor receptor

Fig. 1

Stimulation of MSCs with TNF-α and IL-1β increases the expression of several growth factors. MSCs were stimulated with TNF-α and IL-1β 20 ng/ml each and harvested for RNA extraction after 6 h. mRNA expression of various growth factors (AREG, EGF, HBEGF (all EGFR ligands), FGF2, HGF, IL6, PDGFA, and VEGF) was determined by qPCR, which showed a significant increase of FGF2, HBEGF, HGF and of IL6, and an increase of AREG and EGF. Values were normalized to ACTB and GAPDH reference genes. Box and whiskers represent median, interquartile range and minimum and maximum for n = 4 obtained from three different donors; (*) p < 0.05

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us