| ICS (n = 51) | Placebo (n = 24) |
---|---|---|
Gender (M/F) (n) | 45/6 | 20/4 |
Age (yr) | 61.7 (7.8) | 59.4 (8.1) |
Smoking (y/n) (n) | 33/18 | 17/7 |
Packyears (yr) | 48 (31–56) | 42 (34–54) |
Post-bronchodilator FEV1 (% pred) | 62.5 (9.2) | 61.2 (8.3) |
Post-bronchodilator FEV1 (L) | 2.02 (0.41) | 2.00 (0.55) |
Post-bronchodilator FEV1/IVC (%) | 47.3 (8.8) | 46.7 (9.0) |
Serum YKL-40 (ng/ml) | 66 (49–119) | 78 (60–118) |
Sputum YKL-40 (ng/ml) | 52 (20–79) | 18 (12–40) |