Impaired cardiac and peripheral hemodynamic responses to inhaled β2-agonist in cystic fibrosis

Respiratory Research

Table 2 Heart rate and peripheral vascular function

	Minutes after albuterol
	Baseline	30 min	60 min
Variable
Heart rate (beats/min)
CF	88±4	92±4	92±4
CTL	74±2*	77±2*	76±2*
Systolic blood pressure (mm Hg)
CF	104±2	104±2	103±2
CTL	109±2	107±2	108±2
Diastolic blood pressure (mm Hg)
CF	70±3	67±3	68±3
CTL	72±2	68±1	70±1
Mean arterial pressure (mm Hg)
CF	82±2	76±3	80±2
CTL	84±1	81±1	83±1
SVR (dynes·sec/cm⁵)
CF	1415±94	1276±96	1337±106
CTL	1301±60†	1095±50	1044±50*
SVR_I (dynes·sec/cm⁵/m²)
CF	837±61	756±63	794±72
CTL	720±39^†	603±30*	577±31*

Data presented as means±SEM. CF cystic fibrosis (n=18), CTL healthy individuals (n=30), SVR systemic vascular resistance, SVR _I, systemic vascular resistance index; *CF vs. CTL, p<0.05; ^†baseline vs. 60 min, p<0.05

ISSN: 1465-993X