Fig. 3

Uridine supplementation inhibits inflammation and fibrosis following chronic bleomycin administration. Animals were treated with i. p. bleomycin twice a week over a time period of 4 weeks. Starting from day 14 on animals received either uridine or vehicle for 3 times a week. Animals were assessed for inflammation and fibrosis at day 30. a BALF differential cell counts. b BALF cytokine levels. c HE stainings of lung sections. d BALF collagen content. e Collagen content on histological lung slides. Data are means ± SEM, n = 4–9 mice per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0,0001. The experiment was repeated once with similar results