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Table 2 IC50 values calculated from sigmoidal curve fitting of dexamethasone inhibition

From: The effects of corticosteroids on COPD lung macrophages: a pooled analysis

 

TNF-α

IL-6

CXCL8

 

NS

S

COPD

NS

S

COPD

NS

S

COPD

IC50 (nM)

7.3

3.7

3.4

10.4

9.6

6.2

N/C

5.0

21.0

  1. Data is presented from inhibition of TNF-α, IL-6 and CXCL8 from never smokers (NS), smokers (S) and COPD patients
  2. N/C not calculated