Fig. 5
From: Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells
AKT phosphorylation stimulated by PDGF is not reduced in Plk1 KD smooth muscle cells. Stable Plk1 KD cells and cells expressing control shRNA were treated with 20 ng/ml PDGF for 10 min, or left untreated. a Representative immunoblots illustrating the effects of Plk1 KD on AKT phosphorylation. b Basal and the PDGF-induced AKT phosphorylation (Ser-473) is similar in Plk1 KD cells and cells producing control shRNA (P > 0.05). Stimulated AKT phosphorylation was normalized to the basal level of cells expressing control shRNA. Values are mean ± SE (n = 4)