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Fig. 4 | Respiratory Research

Fig. 4

From: 6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFκB activation in airway epithelial cells

Fig. 4

6-MP decreases Muc5ac mucin gene expression. a Serum-starved NCI-H292 cells were treated with a NFκB inhibitor and then stimulated with TNFα. RT-PCR was performed to assess mRNA expression of Muc5ac. b-c Serum-starved NCI-H292 cells were pre-treated with 6-MP and then stimulated with TNFα, and RT-PCR was performed to assess mRNA expression of Muc5ac (b) and Muc2 (c). Values represent mean ± S.D. *, p ≤ 0.05. d Muc5ac protein expression was determined by immunofluorescence using the appropriate antibody, and Hoechst was used for nuclear staining. a.u = arbitrary units

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Respiratory Research

ISSN: 1465-993X

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