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Table 3 Biomarker levels at exacerbation and 4 weeks follow-up

From: Accelerated extracellular matrix turnover during exacerbations of COPD

  Exacerbation (ng/ml) Follow-up (ng/ml) P value
C3M 29.24 [26.32–32.49] 22.64 [20.78–24.67] <0.0001
C4M 95.96 [85.83–107.28] 73.30 [66.59–80.69] <0.0001
C6M 19.78 [16.82–23.27] 13.27 [11.56–15.23] <0.0001
ELM7 4.26 [3.90–4.64] 3.61 [3.37–3.87] <0.0001
EL-NE 7.79 [6.30–9.63] 5.23 [4.41–6.21] <0.0001
VCANM 1.69 [1.58–1.80] 1.87 [1.78–1.97] 0.0001
Pro-C3 12.10 [10.60–13.81] 12.79 [11.35–14.42] 0.2549
P4NP 7S 510.99 [440.91–592.21] 359.20 [312.28–413.17] <0.0001
Pro-C6 5.36 [4.81–5.99] 6.38 [5.71–7.14] <0.0001
  1. Results are presented as geometric mean [95 % confidence interval] and corresponding P values comparing circulating biomarker levels at time of exacerbation and follow-up