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Table 1 Patient characteristics of fibroblast strains derived from lung resection

From: Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression

 

Normal

At Risk

COPD

n of subjects

6

15

12

Age (yr)

66.7 ± 2.6

64 ± 0.7

68.3 ± 0.9

Gender (M/F)

(2/4)

(8/7)

(8/4)

Smoking #

0.0

36.5 ± 1.2

37.6 ± 1.3

FEV 1 (%)

88.2 ± 3.3

88.2 ± 0.9

65.8 ± 2.16

FVC (%)

83 ± 3.4

92 ± 0.9

81.4 ± 2.3

FEV 1 /FVC (%)

88 ± 2.7

76.6 ± 0.5

55.0 ± 1.7***

  1. Results presented as average ± SEM.
  2. #Denotes pack-years.
  3. ***FEV1/FVC of COPD patients was significantly lower (p < 0.05) compared to either the non-smokers or the smokers without COPD, which did not differ from each other.
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Respiratory Research

ISSN: 1465-993X

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