Table 2 General characteristics of population and results of mitochondrial and nucluear DNA analysis
From: Mitochondrial DNA alteration in obstructive sleep apnea
|  | Patients (N = 46) | Controls (N = 36) |  |
|---|---|---|---|
|  | Mean  ±  DS | Mean  ±  DS | p |
General Characteristics | |||
Males (%) | 76 | 73 | 0.67 |
Age (years) | 59.27 ± 11.38 | 54.42 ± 6.63 | 0.08 |
BMI (Kg/m2) | 30.84 ± 3.64 | 29.06 ± 4.7 | 0.07 |
pH | 7.40 ± 0.02 | 7.40 ± 0.01 | 0.60 |
PaO2 (mmHg) | 80.78 ± 11.65 | 71.90 ± 18.00 | 0.13 |
PaCO2 (mmHg) | 40.95 ± 4.45 | 40.42 ± 5.51 | 0.80 |
FVC (%) | 104.89 ± 18.55 | 103.25 ± 14.05 | 0.37 |
FEV1 (%) | 97.60 ± 25.02 | 96.58 ± 11.65 | 0.85 |
FEV1/FVC | 75.37 ± 4.2 | 78.2 ± 6.1 | 0.30 |
Polygraphic Data | |||
AHI (events/h) | 36.63 ± 24.18 | 3.8 ± 1.10 | <0,001 |
ODI (events /h) | 28.51 ± 25.31 | 3,1 ± 1.00 | <0,001 |
T90 (%) | 16.98 ± 22.98 | 1,5 ± 0.31 | <0,001 |
SaO2 Mean (%) | 91.51 ± 5.65 | 95,1 ± 2.42 | <0,001 |
ESS | 11.35 ± 3.68 | 4.3 ± 2.15 | < 0,001 |
Biological Data | |||
MtDNA/nDNA | 150.94 ± 49.14 | 128.96 ± 45.80 | 0.04 |
Ct MtDNA/nDNA | 0.67 ± 0.02 | 0.69 ± 0.03 | 0.01 |
Log MtDNA | 2.16 ± 0.14 | 2.08 ± 0.19 | 0.04 |
ROMs | 329.71 ± 70.17 | 226.00 ± 36.76 | 0.04 |