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Figure 1 | Respiratory Research

Figure 1

From: Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb

Figure 1

Genome-wide analysis of miRNA and mRNA in Nkx2-1-knockdown cells. A. Representative western blot analysis of NKX2-1 protein levels in Nkx2-1-shRNA treated MLE15 cells compared to non-silencing control. These stable cell lines were fully characterized in Cao et al [22], and Tagne et al, [12]. B. Diagram of the transcriptomic analyses indicating the number of genes identified up- or down-regulated (p < 0.05; FDR < 0.2). C. Expression levels of epithelial and mesenchymal markers in Nkx2-1shRNA treated MLE15 cells relative to non-silencing control, determined by microarray analysis. Adjusted p value < 0.0005.

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Respiratory Research

ISSN: 1465-993X

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