Never-smoker (N) | Smoker (S) | COPD (C) | S vs. N | C vs. N | C vs. S | |
---|---|---|---|---|---|---|
n = 21 | n = 21 | n = 54 | p-value | p-value | p-value | |
Systemic inflammation (yes/no) | 1/20 | 9/12 | 27/27 | <0.01 | <0.001 | 0.530 |
Leukocytes (109/l blood) | 6.1 [4.0-9.1] | 8.7 [4.4-13.7] | 8.4 [4.1-13.9] | <0.01 | <0.001 | 0.567 |
CRP (mg/l blood) | 1.0 [1.0-8.2] | 3.7 [1.0-14.8] | 3.5 [1.0-24.3] | <0.001 | <0.001 | 0.552 |
Fibrinogen (g/l blood) | 3.0 [2.4-4.8] | 3.6 [2.5-5.4] | 4.2 [2.2-6.4] | <0.05 | <0.001 | 0.153 |
Interleukin-6 (pg/ml blood) | 2.17 [1.50-5.62] | 2.42 [1.50-6.94] | 4.19 [1.5-14.4] | 0.362 | <0.001 | <0.01 |
25-OH-Vitamin-D (nmol/l) | 54 [24–112] | 62 [27–108] | 45 [13–115] | 0.443 | 0.294 | 0.059 |