Table 3 Sensitivity and specificity and AUC of 5 identified miRNAs in detecting early-stage NSCLC
From: Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer
MiRNA | Training set (NSCLC vs. Healthy) | Validation set (NSCLC vs. Control) | ||||
|---|---|---|---|---|---|---|
Sensitivity (95% CI) | Specificity (95% CI) | AUC (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | AUC (95% CI) | |
miR-20a | 0.84 [0.76-0.90] | 0.83 [0.71-0.92] | 0.91 [0.86-0.95] | 0.83 [0.74-0.89] | 0.81 [0.72-0.88] | 0.89 [0.85-0.93] |
miR-223 | 0.87 [0.80-0.93] | 0.86 [0.75-0.94] | 0.96 [0.94-0.98] | 0.87 [0.80-0.92] | 0.86 [0.78-0.92] | 0.94 [0.91-0.96] |
miR-21 | 0.70 [0.61-0.78] | 0.68 [0.55-0.80] | 0.79 [0.73-0.86] | 0.67 [0.54-0.72] | 0.68 [0.59-0.77] | 0.77 [0.71-0.83] |
miR-155 | 0.87 [0.80-0.93] | 0.87 [0.75-0.94] | 0.94 [0.91-0.97] | 0.86 [0.78-0.91] | 0.84 [0.76-0.91] | 0.92 [0.89-0.96] |
miR-145 | 0.73 [0.64-0.81] | 0.75 [0.62-0.85] | 0.82 [0.75-0.88] | 0.70 [0.61-0.78] | 0.68 [0.58-0.76] | 0.77 [0.71-0.83] |