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Table 5 Comparison of effect of fluticasone and “other ICS” on outcomes

From: Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis

Outcome

Multivariate hazard ratio

(95% CI)

No ICS

Other ICS

Fluticasone

Primary endpoints

New case diabetes

1.00

0.98 (0.69-1.39)

0.82 (0.58-1.15)

Worsening of existing diabetes

1.00

1.01 (0.72-1.41)

0.84 (0.60-1.17)

Secondary endpoints

Hospitalisation for pneumonia

No carryover

1.00

0.88 (0.68-1.14)

1.23 (1.01-1.51)

180-day carryover

1.00

1.05 (0.79-1.39)

1.50 (1.17-1.91)

Hospitalisation for fracture

1.00

1.08 (0.72-1.60)

1.10 (0.57-2.10)

Cataract related outcome

1.00

1.34 (0.99-1.82)

2.24 (1.40-3.60)