Local association plots for significant loci in the meta-analysis of cases with chronic bronchitis and COPD versus smoking control subjects in COPDGene non-Hispanic whites, GenKOLS, and ECLIPSE. A. rs2869967 on chromosome 4q22.1. B. rs34391416 on 11p15. The x-axis is chromosomal position, and the y-axis shows the –log10 P value. The most significant SNP at each locus is labeled in purple, with other SNPs colored by degree of linkage disequilibrium (r2). Plots were created using LocusZoom.