The effect of CSF-1 administration on lung maturation in a mouse model of neonatal hyperoxia exposure

Respiratory Research

Table 2 Morphometric analysis of lungs from CSF-1-treated mice after 7 days of neonatal hyperoxia exposure

Morphometric estimation of percentage tissue, percentage airspace and mean linear intercept (MLI) at P11 (n = 4 lungs/treatment) and P35 (n = 6-7 lungs/treatment) in newborn mice exposed to normoxia or hyperoxia for 7 days followed by either CSF-1 or PBS treatment for 5 consecutive days. No significant changes were observed in the morphometric parameters examined amongst the three treatment groups. Data were analysed using one-way ANOVAs and Tukey’s post-hoc tests.

ISSN: 1465-993X