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Table 2 Inflammatory mediators in saliva

From: Compartment differences of inflammatory activity in chronic obstructive pulmonary disease

 

Healthy non-smoker

Smokers without COPD

Smokers with COPD

 

IL-8 (pg/ml)

307 (225-558)

262 (208-407)

360 (165-474)

P = 0.512

MMP-9 (ng/ml)

338 (105-679)

170 (62-465)

217 (101-351)

P = 0.437

TIMP-1 (ng/ml)

449 (225-814)

354 (221-535)

360 (241-469)

P = 0.556

MMP-9/TIMP-1

0.54 (0.29-1.16)

0.37 (0.23-1.10)

0.38 (0.27-0.96)

P = 0.789

TNF-α (pg/ml)

2.04 (1.19-3.82)

0.529*** (<0.5-1.25)

0.704*** (<0.5-1.23)

P < 0.001

  1. Results are presented as median and 25th-75th percentiles.
  2. P-values indicate comparisons between groups (Kruskal-Wallis test), bold data indicate significance.
  3. ***indicate P < 0.001 compared with healthy non-smokers (Mann-Whitney U test).