Increased levels of soluble interleukin-6 receptor and CCL3 in COPD sputum

Respiratory Research

Table 2 Sputum cell counts

	COPD	S	HNS	p-value (ANOVA)
Neutrophil%	69.5 (23.8)*	54 (25.1)	38.7 (27.2)	0.0003
Macrophage%	26.6 (23.7)**§	48.7 (28.4)	46.3 (33.1)	0.0033
Eosinophil %^	1.3 (0–23.3)*†	0 (0–1.5)	0 (0–2.5)	<0.0001
Lymphocyte %	0.1 (0.4)	0.1 (0.5)	0.02 (0.06)	ns
TCC*10⁶	3.3 (3.6)**	2.9 (4.4)	0.7 (0.7)	ns
TCC/g*10⁶	3.5 (3)	2.9 (3.2)	2.4 (2.2)	ns
Neutrophil TCC/g*10⁶	2.6 (2.8)*†	0.3 (0.2)	0.3 (0.2)	0.0004
Macrophage TCC/g*10⁶	0.7 (0.7)	0.5 (0.8)	0.4 (0.5)	ns
Eosinophil TCC/g*10^{6^}	0.03 (0–1.5) ‡¶	0 (0–0.02)	0 (0–0.01)	<0.0001
Lymphocyte TCC/g*10⁶	0.003 (0.007)	0.001 (0.002)	0.0001 (0.001)	ns

Data is presented as mean (SD) with the exception of ^{^}eosinophil % and eosinophil TCC/g which are presented as median (range). Explanation of abbreviations: TCC Total cell count, TCC/g Total cell count/gram *p < 0.001 COPD vs HNS, **p < 0.05 COPD vs HNS, §p < 0.05 COPD vs S, †p < 0.001 COPD vs S, ‡p < 0.0001 COPD vs HNS, ¶ p < 0.0001 COPD vs S.

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