Figure 1

Immunocytochemical identification of (a) T cells (CD3) and (b) major basic protein-positive eosinophils in airways that are greater than 2 mm in diameter from patients with asthma. (c) Major basic protein immunostaining of an airway greater than 2 mm in diameter from a nonasthmatic person. (d) EG2-positive cells (activated eosinophils) in an airway less than 2 mm in diameter. (e) T-cell immunostaining in asthmatic airways that are less than 2 mm in diameter. (f) Eosinophil major basic protein immunostaining in lung parenchyma tissue from asthmatic patient. Adapted from Hamid et al. [4].