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Table 1 Alterations in gene expression in response to RSV infection

From: Gene expression in epithelial cells in response to pneumovirus infection

Group

Examples

Cell-surface

ICAM-1 (CD54)

molecules

CD18

 

Vascular cell adhesion molecule (VCAM)

 

Major histocompatibility complex (MHC) I and II

 

CD14

 

CD15

 

Fas

 

Muscarinic receptors

 

β2-adrenergic receptors

 

Lewisx antigen

Chemokines and

IL-8

cytokines

IL-11

 

IL-6

 

Soluble TNF receptor

 

RANTES

 

Monocyte chemoattractant protein (MCP)-1

 

MIP-1α

 

Granulocyte-macrophage colony-stimulating

 

   factor (GM-CSF)

 

IL-1β

 

IFN-β

 

Interleukin-1α

Transcription

NF-κB

factors

NF-IL-6

Others

Inducible nitric oxide synthase (iNOS)

 

Vascular endothelial growth factor (VEGF)/VPF

 

Endothelin-1

 

5-Lipoxygenase

 

Leukotrienes

 

IEX-1L

 

Cytokeratin-17

  1. Increased expression of the these genes and/or gene products has been observed in response to RSV infection of target cells in vitro. VPF, vascular permeability factor.