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Table 1 Biophysical properties of Kv channel α- and β-subunits that are potentially involved in oxygen sensing

From: Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels

Subunit

Channel conductance (pS)

Threshold of activation (mV)

Sensitivity to hypoxia

References

Kv1.2

18

-20

Yes

[24**]

  

-40

Yes

[23*]

Kv1.5

7.1

-50

-

[49]

  

-30

No

[27*]

  

-60

No

[24**]

  

-

Yes

[26]

Kv2.1

8.5

-10

Yes

[20**]

  

-45

No

[23*]

  

-40

Yes

[24**]

Kv3.1b

14-31

-20

Yes

[27*]

Kv4.2

-

-40

Yes

[28*]

Kv1.2/Kv1.5

-

-50

Yes

[24**]

Kv2.1/Kv9.3

14.5

-50

Yes

[20**]

  

-50

Yes

[24**]

Kv4.2/Kvβ1.2

-

-40

Yes

[28*]