From: Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD
Control | Stage II | Stage IV | |
---|---|---|---|
Number of subjects | 5 | 9 | 9 |
Age (years) | 62 (36–63) | 70 (44–81) | 55 (44–61) |
Smoking (Ex/C) | 2/3 | 5/4 | 9/0 |
Pack-years | 13 (0–75) | 30 (8–58) | 30 (17–54) |
FEV1 % predicted | 86 (83–108) | 73 (50–76) | 19 (13–29) |
FEV1/FVC % pred | 73 (70–81) | 55 (37–68) | 35 (24–66) |