Figure 8
From: Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells
ER morphology in uncorrected or corrected CF human tracheal gland cells compared to non CF human tracheal gland cells. A Immunostaining of calreticulin in untreated CF-KM4, MM39 and miglustat (100 μM 2 h) or NB-DGJ (100 μM 2 h) treated CF-KM4 cells. Nuclei are labelled with TOPRO-3, bar = 10 μm. B ER imaging (with ER tracker probes) in untreated or miglustat (100 μM 2 h) or NB-DGJ (100 μM 2 h) treated CF-KM4 cells and in untreated MM39 cells, bar = 10 μm.