Figure 5
From: Bronchiolar chemokine expression is different after single versus repeated cigarette smoke exposure
Repeated CS exposure upregulates KC, MIP-2, TNF-α, and IL-1β expression in whole lung homogenate and in LCM-retrieved bronchiolar epithelium. Mice were repeatedly exposed to CS for up to 10 days, and the expression of KC (A), MIP-2 (B), TNF-α (C), and IL-1β (D) in whole lung homogenates (white bars) and LCM-retrieved bronchiolar epithelium (black bars) were determined by real-time RT-PCR. Data represent the average expression relative to β2-MG ± SEM from at least six mice. Statistical significance: * = p < 0.05; ** = p < 0.01; *** = p < 0.001.