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Table 2 Static and dynamic lung volumes

From: Membrane diffusion- and capillary blood volume measurements are not useful as screening tools for pulmonary arterial hypertension in systemic sclerosis: a case control study

 

SScPAH+ N = 11

SScPAH- N = 13

Control N = 10

FVC, % pred

97.5 ± 20.8

103.0 ± 22.4

122.1 ± 17.0

FEV1, % pred

83.5 ± 12.1

92.5 ± 20.4

108 ± 12.4

FEV1/VC

69.4 ± 9.8

72.8 ± 7.0

74.2 ± 6.3

TLC, % pred

90.3 ± 17.1

91.4 ± 13.6

 

TLCO, % pred

40.7 ± 6.8*

63.3 ± 11.7

93.3 ± 15.0

Dm, mmol·min-1·kPA-1

3.7 ± 1.1*

7.5 ± 2.8

15.1 ± 4.1

Dm,% pred

21.7 ± 5.8*

39.2 ± 12.4

81.3 ± 18.0

Vc, ml

40.2 ± 14.30

45.8 ± 13.7

56.2 ± 16.1

Vc, % pred

59.9 ± 24.6

61.7 ± 17.6

82.8 ± 10.8

Dm%/Vc %

0.41 ± 0.25

0.71 ± 0.37

1.00 ± 0.26

Vc%/Dm %

2.99 ± 1.5*

1.73 ± 0.74

1.06 ± 0.26

  1. Values expressed as mean ± SD. Abbreviations: SScPAH+: systemic sclerosis-associated pulmonary arterial hypertension; SScPAH-: SSc without PAH. FEV1 %: forced expiratory volume, percentage of predicted. TLC: total long capacity. TLCO: transfer factor of the lung for carbon monoxide. Dm: diffusing capacity of the alveolar capillary membrane. Vc: pulmonary capillary volume. * p < 0.05 for comparison of SScPAH+ with SScPAH-; p < 0.05 for comparison of SScPAH+ with control. p < 0.05 for comparison of SScPAH- with control