Quantification of bead binding and internalization. Adherent GM-MØ were pretreated with either poly(I) (A) or cytochalasin D (B and C) before incubation with fluorescent latex beads. Cells were analyzed for total bead binding (A and B) and percent internalization (C). Bars represent the means of four (A) or three (B and C) donors +/- the standard deviation. For each donor, three fields from each of three replicate wells were analyzed. *p < 0.01 **p < 0.001 when compared to either the control or DMSO conditions.