Effect of PI-3K inhibitors on SR mediated phagocytosis. Adherent GM-MØ were pretreated with wortmannin (A) or LY294002 (B) before being fed fluorescent latex beads. Cells were analyzed for the percent internalization of bound beads. Bars represent the means of five (A) or three (B) donors +/- the standard deviation. For each donor, three fields from each of three replicate wells were analyzed. **p < 0.001 when compared to either the control or DMSO conditions. *p < 0.05 when compared to the control condition.