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Table 2 Main characteristics of the 5 patients with idiopathic bonchiectasis bearing a missense mutation in ENaCβ gene

From: Could a defective epithelial sodium channel lead to bronchiectasis

  Age (years) Sex BMI (Kg.m-2) FEV1 (%pred.) CFTR mutation ENaCβ mutation Sweat Cl- (mmol/L) Basal PD (mV)
Group 1 66 F 22 77 IVS8-5T p.Ser82Cys 44 - 13
  62 F 19 89 F508del p.Ser82Cys 38 - 8
  35 F 23 86 none p.Pro369Thr 22 - 43
  60 F 21 93 none p.Asn288Ser 57 - 10
Group 2 67 M 20 80 IVS8-5T p.Ser82Cys 28 - 22
  1. F : female, M : male, BMI : body mass index, FEV1 : forced expiratory volume in 1 second, pred : predicted, PD : nasal potential difference.