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Table 1 Chitinase expression in three different strains of rats infected with C. neoformans

From: Pulmonary cryptococcosis induces chitinase in the rat

  TH bias** BAL LUNG
   PBS INFECTED PBS INFECTED
Fischer 1 [3,11] 1.8 ± 0.4 11.9 ± 2.6* 2.1 ± 0.3 10.6 ± 1.3*
Sprague Dawley Outbred, Non-biased [12,20] 1.8 ± 0.5 15.2 ± 4.4* 0.7 ± .01 6.4 ± 1.0*
Brown Norway 2 [12,20] 1.9 ± 0.5 6.6 ± 3.9* 1.4 ± .03 5.1 ± 1.7*
  1. Chitinase activity (units × 10-3/ml) in different rat strains following experimental pulmonary cryptococcal infection. Values represent means ± 1 SD. For all experiments 4–5 animals were used per group and measurements done at 2 weeks. * P < 0.05 for comparison between infected tissues and PBS-inoculated controls. **TH bias of rat strain reflects tendency to develop TH1 (cellular) versus TH2 (humoral/allergic) inflammation in response to infection or antigen challenge.