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Figure 9 | Respiratory Research

Figure 9

From: Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone

Figure 9

Influence of methyl prednisolone on the nuclear DNA fragmentation ofL. pneumophila-infected A549 cells. Cells were pre-treated with and without methyl prednisolone (53.4 μM) for one day, and subsequently stimulated. After a 2-day incubation, nuclear DNA fragmentation stained by the TUNEL method was analyzed by flow cytometry. The nuclear DNA fragmentation of virulent strain AA100jm-infected cells without (A) and with methyl prednisolone (B), is shown with no-pretreatment/no-stimulation cells (control) (C), and 30 μM mitomycin C-exposed cells without (D) and with methyl prednisolone (E). FS indicates the cell sizes. m-P; methyl prednisolone.

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Respiratory Research

ISSN: 1465-993X

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