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Figure 2 | Respiratory Research

Figure 2

From: Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone

Figure 2

Cytotoxic effect ofL. pneumophilaon A549 cells. A549 cells were infected with L. pneumophila virulent AA100jm and avirulent dotO mutant strains. LDH levels in the cell supernatants showed a time-dependent change after infection with L. pneumophila at an MOI of 20 (A), and an MOI dose-response relationship 2 days after infection (B). Symbols : ▫, virulent strain AA100jm; ▪, avirulent strain dotO mutant. Data are mean ± SD of three wells. * P < 0.05.

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