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Table 3 Molecular analysis for sodA among sarcoidosis and control specimens

From: Superoxide dismutase A antigens derived from molecular analysis of sarcoidosis granulomas elicit systemic Th-1 immune responses

Patient

Age, Sex, Racea

Biopsy site

Pathologic diagnosis

Presence of granuloma

Tissue storageb

PCR analysisc

sodA region(s)

Sarcoid 1

31, M, C

Lung

Sarcoidosis

Yes

Frozen

Mtb complex

4, 5

Sarcoid 2

46, F, C

Lymph node

Sarcoidosis

Yes

Frozen

GDM

4

Sarcoid 3

65, M, U

Lymph node

Sarcoidosis

Yes

Frozen

Mtb complex

2, 4

Sarcoid 4

29, F, C

Lymph node

Sarcoidosis

Yes

FFPE

-

-

Sarcoid 5

36, F, AA

Lung

Sarcoidosis

Yes

Frozen

Mtb complex

4

Sarcoid 6

48, F, AA

Skin

Sarcoidosis

Yes

FFPE

Mtb complex

3

Sarcoid 7

30, M, AA

Skin

Sarcoidosis

Yes

Frozen

Mtb complex

5

Sarcoid 8

33, F, C

Lymph node

Sarcoidosis

Yes

FFPE

Mtb complex

4

Sarcoid 9

50, F, AA

Lymph node

Sarcoidosis

Yes

FFPE

-

-

Sarcoid 10

50, M, C

Lymph node

Sarcoidosis

Yes

FFPE

Mtb complex

5

Sarcoid 11

41, F, C

Lymph node

Sarcoidosis

Yes

FFPE

-

-

Sarcoid 12

39, M, C

Lymph node

Sarcoidosis

Yes

FFPE

-

-

Sarcoid 13

46, M, AA

Lymph node

Sarcoidosis

Yes

FFPE

Mtb complex

5

Sarcoid 14

45, M, C

Skin

Sarcoidosis

Yes

FFPE

Mtb complex

2

Sarcoid 15

34, F, C

Lymph node

Sarcoidosis

Yes

FFPE

GDM

4

Sarcoid 16

28, M, C

Lymph node

Sarcoidosis

Yes

Frozen

-

-

Sarcoid 17

34, M, C

Lymph node

Sarcoidosis

Yes

FFPE

Mtb complex

2

Control 1

70, F, C

Colon

Normal colon

No

Frozen

-

-

Control 2

22, F, C

Lymph node

Histoplasmosis

Yes

Frozen

Mtb complex

4, 5

Control 3

60, M, C

Lymph node

Nocardia

Yes

Frozen

-

-

Control 4

56, F, C

Lymph node

Cholangial carcinoma

No

Frozen

-

-

Control 5

49, M, C

Lymph node

Nonspecific Interstitial Pneumonia

No

Frozen

-

-

Control 6

11, F, AA

Skin

Blastomycosis

Yes

FFPE

-

-

Control 7

51, F, C

Lung

Histoplasmosis

Yes

FFPE

-

-

Control 8

26, M, C

Lung

Histoplasmosis

Yes

FFPE

-

-

Control 9

30, M, C

Lung

Blastomycosis

Yes

FFPE

-

-

Control 10

25, M, C

Skin

Blastomycosis

Yes

FFPE

-

-

Control 11

26, M, C

Skin

Blastomycosis

Yes

FFPE

-

-

Control 12

36, M, U

Lung

Hodgkin's lymphoma

No

Frozen

-

-

Control 13

15, M, U

Lymph node

Hodgkin's lymphoma

No

Frozen

-

-

Control 14

68, M, C

Lymph node

Sinus histiocytosis

No

Frozen

-

-

Control 15

47, F, C

Lymph node

Histoplasmosis

Yes

FFPE

-

-

Control 16

35, F, C

Lung

Cryptococcus

Yes

FFPE

Mtb complex

4

TB 1

30, M, C

Lymph node

Tuberculosis

Yes

FFPE

Mtb complex

3, 5

TB 2

46, M, C

Knee

Tuberculosis

Yes

FFPE

Mtb complex

2, 4, 5

TB 3

36, M, H

Lymph node

Tuberculosis/AIDS

Yes

FFPE

Mtb complex

1 – 6

  1. aC-Caucasian, AA-African American, H-Hispanic, U-Unknown; bFFPE – formalin-fixed, paraffin-embedded cGDM – genetically distinct mycobacteria
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Respiratory Research

ISSN: 1465-993X

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