Table 6 Mean (SE) FEV1 %predicted in relation to AAT quintile classes in current smokers †
Quintile classes of AAT (g/l) | |||||||
|---|---|---|---|---|---|---|---|
Q0 (≤ 0.9) | Q1 (≥0.9–<1.13) | Q2 (≥1.13, <1.22) | Q3 (≥1.22, <1.31) | Q4 (≥1.31, <1.41) | Q5 (≥1.41) | ptrend from model not including Q0 | |
Men (n) | 13 | 105 | 72 | 109 | 125 | 114 | |
FEV1 (% predicted), CRP adj.† | 95.1 (3.8) | 92.8 1.4) | 93.8 (1.7) | 93.4 (1.3) | 93.2 (1.2) | 95.4 (1.4) | 0.30 |
FEV1 (% predicted), no CRP adj.* | 95.6 (3.8) | 93.3 (1.4) | 94.1 (1.7) | 93.8 (1.3) | 93.3 (1.2) | 94.3 (1.3) | 0.71 |
Men ≥15 cigs/day (n) | 6 | 47 | 33 | 72 | 72 | 87 | |
FEV1 (% predicted), CRP adj.† | 95.3 (5.7) | 89.3 (2.1) | 93.3 (2.5) | 91.2 (1.7) | 93.7 (1.6) | 95.5 (1.6) | 0.04 |
FEV1 (% predicted), no CRP adj.* | 89.7 (2.1) | 89.7 (2.1) | 93.3 (2.5) | 91.4 (1.7) | 93.8 (1.7) | 94.9 (1.6) | 0.07 |
Men <15 cigs/day (n) | 7 | 58 | 39 | 37 | 53 | 27 | |
FEV1 (% predicted), CRP adj.† | 96.5 (5.0) | 96.0 (1.8) | 94.3 (2.2) | 96.6 (2.2) | 92.99 (1.9) | 94.1 (2.8) | 0.38 |
FEV1 (% predicted), no CRP adj.* | 97.3 (2.2) | 96.7 (1.7) | 95.2 (2.2) | 97.0 (2.2) | 92.5 (1.9) | 91.1 (2.6) | 0.05 |
Women (n) ¶ | 9 | 36 | 39 | 69 | 98 | 166 | |
FEV1 (% predicted), CRP adj.† | 98.6 (4.5) | 94.6 (2.3) | 96.8 (2.2) | 94.1 (1.6) | 95.9 (1.3) | 96.7 (1.1) | 0.24 |
FEV1 (% predicted), no CRP adj.* | 98.6 (4.5) | 95.5 (2.3) | 92.2 (2.2) | 94.9 (1.6) | 96.4 (1.4) | 95.5 (1.1) | 0.99 |
Premenopausal (n) | 4 | 21 | 21 | 32 | 40 | 81 | |
FEV1 (% predicted), CRP adj.† | 98.8 (6.2) | 96.1 (2.7) | 95.4 (2.7) | 97.0 (2.2) | 100.2 (2.0) | 94.6 (1.4) | 0.71 |
FEV1 (% predicted), no CRP adj.* | 98.8 (6.2) | 96.7 (2.7) | 95.3 (2.2) | 99.0 (1.9) | 101.0 (1.9) | 93.6 (1.4) | 0.64 |
Postmenopausal (n) | 5 | 15 | 18 | 37 | 58 | 85 | |
FEV1 (% predicted), CRP adj.† | 98.3 (6.4) | 91.7 (3.7) | 97.7 (3.4) | 92.4 (2.3) | 92.3 (1.8) | 99.2 (1.6) | 0.15 |
FEV1 (% predicted), no CRP adj.* | 97.1 (6.6) | 93.7 (3.7) | 99.6 (3.4) | 93.5 (2.4) | 92.7 (1.9) | 97.7 (1.6) | 0.69 |
Postmenopausal, ≥ 15 cigs/day (n))¶ | 4 | 8 | 7 | 19 | 31 | 53 | |
FEV1 (% predicted), CRP adj.† | 94.6 (8.3) | 84.7 (5.5) | 90.0 (6.0) | 87.9 (3.6) | 90.0 (2.7) | 96.3 (2.2) | 0.05 |
FEV1 (% predicted), no CRP adj.* | 93.9 (8.5) | 87.4 (2.2) | 92.7 (6.2) | 88.1 (3.7) | 90.4 (2.9) | 95.1 (2.2) | 0.22 |
Postmenopausal, <15 cigs/day (n)¶ | 1 | 7 | 11 | 18 | 27 | 32 | |
FEV1 (% predicted), CRP adj.† | 105.4 (12.3) | 100.2 (4.6) | 103.6 (3.8) | 98.4 (3.0) | 96.2 (2.3) | 102.3 (2.4) | 0.85 |
FEV1 (% predicted), no CRP adj.* | 108.8 (12.6) | 100.2 (4.7) | 103.5 (3.8) | 99.1 (3.0) | 96.7 (2.3) | 101.3 (2.2) | 0.93 |