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Table 6 Mean (SE) FEV1 %predicted in relation to AAT quintile classes in current smokers †

From: Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function

  Quintile classes of AAT (g/l)
  Q0 (≤ 0.9) Q1 (≥0.9–<1.13) Q2 (≥1.13, <1.22) Q3 (≥1.22, <1.31) Q4 (≥1.31, <1.41) Q5 (≥1.41) ptrend from model not including Q0
Men (n) 13 105 72 109 125 114  
FEV1 (% predicted), CRP adj.† 95.1 (3.8) 92.8 1.4) 93.8 (1.7) 93.4 (1.3) 93.2 (1.2) 95.4 (1.4) 0.30
FEV1 (% predicted), no CRP adj.* 95.6 (3.8) 93.3 (1.4) 94.1 (1.7) 93.8 (1.3) 93.3 (1.2) 94.3 (1.3) 0.71
Men ≥15 cigs/day (n) 6 47 33 72 72 87  
FEV1 (% predicted), CRP adj.† 95.3 (5.7) 89.3 (2.1) 93.3 (2.5) 91.2 (1.7) 93.7 (1.6) 95.5 (1.6) 0.04
FEV1 (% predicted), no CRP adj.* 89.7 (2.1) 89.7 (2.1) 93.3 (2.5) 91.4 (1.7) 93.8 (1.7) 94.9 (1.6) 0.07
Men <15 cigs/day (n) 7 58 39 37 53 27  
FEV1 (% predicted), CRP adj.† 96.5 (5.0) 96.0 (1.8) 94.3 (2.2) 96.6 (2.2) 92.99 (1.9) 94.1 (2.8) 0.38
FEV1 (% predicted), no CRP adj.* 97.3 (2.2) 96.7 (1.7) 95.2 (2.2) 97.0 (2.2) 92.5 (1.9) 91.1 (2.6) 0.05
Women (n) 9 36 39 69 98 166  
FEV1 (% predicted), CRP adj.† 98.6 (4.5) 94.6 (2.3) 96.8 (2.2) 94.1 (1.6) 95.9 (1.3) 96.7 (1.1) 0.24
FEV1 (% predicted), no CRP adj.* 98.6 (4.5) 95.5 (2.3) 92.2 (2.2) 94.9 (1.6) 96.4 (1.4) 95.5 (1.1) 0.99
Premenopausal (n) 4 21 21 32 40 81  
FEV1 (% predicted), CRP adj.† 98.8 (6.2) 96.1 (2.7) 95.4 (2.7) 97.0 (2.2) 100.2 (2.0) 94.6 (1.4) 0.71
FEV1 (% predicted), no CRP adj.* 98.8 (6.2) 96.7 (2.7) 95.3 (2.2) 99.0 (1.9) 101.0 (1.9) 93.6 (1.4) 0.64
Postmenopausal (n) 5 15 18 37 58 85  
FEV1 (% predicted), CRP adj.† 98.3 (6.4) 91.7 (3.7) 97.7 (3.4) 92.4 (2.3) 92.3 (1.8) 99.2 (1.6) 0.15
FEV1 (% predicted), no CRP adj.* 97.1 (6.6) 93.7 (3.7) 99.6 (3.4) 93.5 (2.4) 92.7 (1.9) 97.7 (1.6) 0.69
Postmenopausal, ≥ 15 cigs/day (n)) 4 8 7 19 31 53  
FEV1 (% predicted), CRP adj.† 94.6 (8.3) 84.7 (5.5) 90.0 (6.0) 87.9 (3.6) 90.0 (2.7) 96.3 (2.2) 0.05
FEV1 (% predicted), no CRP adj.* 93.9 (8.5) 87.4 (2.2) 92.7 (6.2) 88.1 (3.7) 90.4 (2.9) 95.1 (2.2) 0.22
Postmenopausal, <15 cigs/day (n) 1 7 11 18 27 32  
FEV1 (% predicted), CRP adj.† 105.4 (12.3) 100.2 (4.6) 103.6 (3.8) 98.4 (3.0) 96.2 (2.3) 102.3 (2.4) 0.85
FEV1 (% predicted), no CRP adj.* 108.8 (12.6) 100.2 (4.7) 103.5 (3.8) 99.1 (3.0) 96.7 (2.3) 101.3 (2.2) 0.93