Quintile classes of AAT (g/l) | |||||||
---|---|---|---|---|---|---|---|
Q0 (<0.9) | Q1 (≥0.9–<1.13) | Q2 (≥1.13, <1.22) | Q3 (≥1.22, <1.31) | Q4 (≥1.31, <1.41) | Q5 (≥1.41) | ptrend from model not including Q0 | |
All (n) ¶ | 152 | 952 | 832 | 932 | 764 | 817 | |
FEV1 (% predicted) CRP adj. | 99.8 (1.2) | 98.0 (0.5) | 98.3 (0.5) | 98.1 (0.5) | 97.6 (0.5) | 96.6 (0.5) | 0.28 |
FEV1 (% predicted), no CRP adj. * | 100.4 (1.2) | 98.7 (0.5) | 98.7 (0.5) | 98.2 (0.5) | 97.4 (0.5) | 95.5 (0.5) | <0.001 |
Men (n)‡ | 79 | 627 | 511 | 460 | 351 | 256 | |
FEV1 (% predicted) CRP adj. | 99.0 (1.6) | 96.7 (0.6) | 97.3 (0.6) | 97.2 (0.6) | 95.8 (0.8) | 93.8 (1.0) | 0.08 |
FEV1 (% predicted), no CRP adj. * | 99.3 (1.6) | 97.3 (0.6) | 97.6 (0.6) | 97.1 (0.7) | 95.4 (0.8) | 92.6 (0.9) | <0.001 |
Women (n) ¶, ‡ | 73 | 325 | 321 | 472 | 413 | 561 | |
FEV1 (% predicted) CRP adj. | 100.6 (1.6) | 99.4 (0.8) | 99.2(0.8) | 99.3(0.7) | 99.2 (0.7) | 98.8 (0.6) | 0.76 |
FEV1 (% predicted), no CRP adj. * | 101.4 (1.7) | 99.9 (0.8) | 99.7(0.8) | 99.5(0.7) | 99.3 (0.7) | 97.8 (0.6) | 0.19 |
Never/Former Smokers (n) ¶, ‡ | 130 | 811 | 721 | 754 | 541 | 537 | |
FEV1 (% predicted), CRP adj. | 100.4 (1.3) | 99.1 (0.5) | 99.0 (0.5) | 99.1 (0.5) | 98.4 (0.6) | 96.9 (0.7) | 0.10 |
FEV1 (% predicted), no CRP adj.* | 100.9 (1.3) | 99.6 (0.5) | 99.3 (0.5) | 99.1 (0.5) | 98.2 (0.6) | 95.9 (0.7) | <0.001 |
Current Smokers (n) ¶, ‡ | 22 | 141 | 111 | 178 | 223 | 280 | |
FEV1 (% predicted), CRP adj. | 96.9 (2.9) | 93.6 (1.2) | 95.0 (1.3) | 93.8 (1.0) | 94.5 (0.9) | 95.6 (0.9) | 0.16 |
FEV1 (% predicted), no CRP adj.* | 97.2 (2.9) | 94.3 (1.0) | 95.7 (1.3) | 94.3 (1.0) | 94.7 (0.9) | 94.5 (0.9) | 0.91 |
Currents Smokers ≥15 cigs/d (n) ¶,‡ | 11 | 60 | 48 | 103 | 122 | 182 | |
FEV1 (% predicted), CRP adj. | 96.5 (4.3) | 88.8 (1.9) | 93.6 (2.1) | 91.2 (1.4) | 93.6 (1.3) | 95.3 (1.1) | 0.01 |
FEV1 (% predicted), no CRP adj.* | 96.7 (4.3) | 89.7 (1.9) | 94.4 (1.1) | 91.2 (1.4) | 93.9 (1.3) | 94.4 (1.1) | 0.06 |
Currents Smokers <15 cigs/d (n) ¶,‡ | 11 | 81 | 63 | 75 | 101 | 98 | |
FEV1 (% predicted), CRP adj. | 99.6 (3.9) | 98.3 (1.5) | 96.9 (1.7) | 96.6 (1.5) | 95.8 (1.3) | 94.9 (1.5) | 0.21 |
FEV1 (% predicted), no CRP adj.* | 99.9 (3.9) | 98.9 (1.5) | 97.6 (1.4) | 97.2 (1.5) | 95.9 (1.3) | 93.5 (1.4) | 0.02 |