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Table 1 Baseline characteristics for fluticasone and placebo groups.

From: Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial

  Patients (n = 260)
  Fluticasone n = 128 Placebo n = 132
Age (years) (a) 67.6 (8.9) 67.3 (9.0)
Male n (%) (b) 62 (48%) 74 (56%)
Exacerbation history   
   Self-reported yearly COPD exacerbation rate 1.93 (1.52) 1.86 (1.57)
   Antibiotics or steroids in last year(c) 1.59 (1.71) 1.48 (1.77)
Smoking Status   
   Current smoker n (%) 52 (40.6%) 47 (35.6%)
   Amount smoked (pack years) 40.0 (24.2) 38.8 (22.3)
Medications   
   Duration of inhaled medications (years) 8.7 (7.0) 8.2 (5.6)
   Daily Prescribed Dosage of ICS(d) (mcg) 947 (784) 812 (531)
   On LABA medication n (%) 45 (35.1%) 42 (31.8%)
   Influenza vaccine in winter 104 (81.2%) 106 (80.3%)
Lung Function   
   Pre bronchodilator FEV1 (litres) 1.22 (0.54) 1.32 (0.54)
   Post bronchodilator FEV1 (litres) 1.31 (0.55) 1.40 (0.56)
   Post bronchodilator FEV1 (% predicted) 53.2 (18.2) 55.0 (17.1)
   Reversibility (% change in FEV1) 8.1 (8.0) 7.2 (6.8)
   Post bronchodilator FVC (litres) 2.40 (0.77) 2.56 (0.88)
   Peak expiratory flow rate (L/min) 220 (90) 235 (90)
Health Related Quality of Life   
   SGRQ Total (%) 52.6 (20.2) 47.2 (19.4)
   EuroQol 5D total score 0.64 (0.29) 0.68 (0.30)
   EuroQol 5D visual analogue scale 60.6 (18.8) 61.1 (20.8)
MRC Dyspnoea Scale   
   Scale 3 or greater (%) 77 (60%) 66 (50%)
Chronic Symptom Profile (d)   
   Shortness of Breath n (%) 96 (75%) 95 (72%)
   Sputum Production n (%) 69 (54%) 78 (59%)
   Wheeze n (%) 60 (47%) 59 (45%)
   Cough n (%) 72 (56%) 69 (53%)
  1. (a) Continuous data is displayed as mean value and standard deviation.
  2. (b) Categorical data is displayed as number of cases (n) and percentage of group for fluticasone or placebo.
  3. (c) Patient prescriptions at general practice/hospital/accident and emergency/outpatient visits for antibiotics and/or steroids for COPD exacerbation.
  4. (d) Dosage of daily inhaled corticosteroid prescribed is stated a s beclomethasone equivalent in micrograms.
  5. (e) Chronic symptom profile at recruitment interview. LABA = Long acting beta 2 agonist.